Endophytic bacteria isolated from higher plant in Aceh, Indonesia, and their chemical compounds activity against Fusarium oxysporum f. sp. lycopersici

Abstract Background Endophytic bacteria are an association between and plant tissue that could play a role as biocontrol agent. Main body were isolated from several high root plants in Aceh, Indonesia. This study aimed to detect the chemical compounds of potential endophytic agent against Fusarium oxysporum f. sp. lycopersici (FOL). There 198 bacterial isolates detected roots 9 higher plant. The hypersensitive reaction showed 193 non-pathogenic. 13 worked inhibit FOL 50.0 89.2%; such Solanum lycopersicum L., Psidium guajava Dendrocalamus asper (Schult with f.) Backer ex Heyne, Pinus merkusii Theobroma cacao Albizia chinensis L. Molecular identification using 16S rRNA gene sequence confirmed derived species Pseudomonas aeruginosa , P. mosselii Arthrobacter sp., Bacillus cereus B. thuringiensis Serratia marcescens . highest inhibition was analyzed GC-MS analysis. analysis identified antibiotics Pyrrolo [1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)- produced by succeeded suppressing FOL. Conclusion recommends effective for control pathogen.